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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ARHGDIA
All Species:
17.27
Human Site:
Y133
Identified Species:
34.55
UniProt:
P52565
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.27
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P52565
NP_004300.1
204
23207
Y133
M
K
Y
I
Q
H
T
Y
R
K
G
V
K
I
D
Chimpanzee
Pan troglodytes
XP_001164704
183
21106
R113
K
Y
I
Q
H
T
Y
R
K
G
V
K
I
D
K
Rhesus Macaque
Macaca mulatta
XP_001112043
178
20308
V108
S
F
V
L
K
E
G
V
E
Y
R
I
K
I
S
Dog
Lupus familis
XP_849933
204
23375
Y133
M
K
Y
I
Q
H
T
Y
R
K
G
V
K
I
D
Cat
Felis silvestris
Mouse
Mus musculus
Q99PT1
204
23389
Y133
M
K
Y
I
Q
H
T
Y
R
K
G
V
K
I
D
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515491
219
25235
Y148
L
K
Y
L
H
H
T
Y
R
K
G
L
R
V
D
Chicken
Gallus gallus
NP_001074340
204
23256
F133
L
K
Y
I
Q
H
T
F
R
K
G
V
K
I
V
Frog
Xenopus laevis
NP_001085674
204
23448
Y133
L
R
Y
Q
Q
Q
T
Y
R
K
G
V
R
L
D
Zebra Danio
Brachydanio rerio
NP_998626
203
23057
F132
L
K
Y
V
Q
Q
T
F
R
K
G
V
R
I
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q20496
191
21900
K121
S
G
L
H
Y
K
H
K
V
K
R
S
G
I
T
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SFC6
240
27213
W168
L
R
Y
T
N
T
V
W
K
T
G
V
K
V
D
Baker's Yeast
Sacchar. cerevisiae
Q12434
202
23120
K131
L
R
Y
V
Q
Y
I
K
K
A
G
I
A
V
D
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
89.7
87.2
97.5
N.A.
97
N.A.
N.A.
62
91.1
78.4
81.3
N.A.
N.A.
N.A.
37.7
N.A.
Protein Similarity:
100
89.7
87.2
99.5
N.A.
99.5
N.A.
N.A.
76.2
97.5
88.2
91.1
N.A.
N.A.
N.A.
52.9
N.A.
P-Site Identity:
100
0
13.3
100
N.A.
100
N.A.
N.A.
60
80
60
66.6
N.A.
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
100
6.6
33.3
100
N.A.
100
N.A.
N.A.
93.3
93.3
86.6
93.3
N.A.
N.A.
N.A.
13.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
33.3
39.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
50.4
61.2
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
33.3
26.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
66.6
73.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
9
0
0
9
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
9
67
% D
% Glu:
0
0
0
0
0
9
0
0
9
0
0
0
0
0
0
% E
% Phe:
0
9
0
0
0
0
0
17
0
0
0
0
0
0
0
% F
% Gly:
0
9
0
0
0
0
9
0
0
9
75
0
9
0
0
% G
% His:
0
0
0
9
17
42
9
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
9
34
0
0
9
0
0
0
0
17
9
59
0
% I
% Lys:
9
50
0
0
9
9
0
17
25
67
0
9
50
0
9
% K
% Leu:
50
0
9
17
0
0
0
0
0
0
0
9
0
9
0
% L
% Met:
25
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
9
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
17
59
17
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
25
0
0
0
0
0
9
59
0
17
0
25
0
0
% R
% Ser:
17
0
0
0
0
0
0
0
0
0
0
9
0
0
9
% S
% Thr:
0
0
0
9
0
17
59
0
0
9
0
0
0
0
9
% T
% Val:
0
0
9
17
0
0
9
9
9
0
9
59
0
25
9
% V
% Trp:
0
0
0
0
0
0
0
9
0
0
0
0
0
0
0
% W
% Tyr:
0
9
75
0
9
9
9
42
0
9
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _